TRPM2 Agonist
-
2′-Deoxy-ADPR
0 ImagesCat. No.: HY-137704CAS No.: 111864-49-42′-Deoxy-ADPR is an endogenous TRPM2 agonist that activates Ca2+-permeable cation channels. 2′-Deoxy-ADPR activates the Ca2+ sensitivity of TRPM2, increasing whole-cell currents by slowing inactivation and increasing open probability. 2′-Deoxy-ADPR can be used in research related to TRPM2 channel-mediated diseases, such as inflammation and immune-related diseases.
-
2'-Deoxyadenosine-5'-O-diphosphoribose sodium
0 ImagesCat. No.: HY-1814812'-Deoxyadenosine-5'-O-diphosphoribose sodium is a TRPM2 agonist. 2'-Deoxyadenosine-5'-O-diphosphoribose sodium enhances calcium-induced currents in inside-out patch-clamp experiments using HEK293 cells expressing human TRPM2. 2'-Deoxyadenosine-5'-O-diphosphoribose sodium is a substrate for Nucleoside Triphosphate Diphosphatase 9 (NUDT9).
